A Danish study examined 109 individuals with severe obesity who underwent an 8-week total diet replacement (800 kcal/day) and achieved an average weight loss of 13.1 kg. Afterward, participants were divided into four groups for a one-year maintenance phase: exercise, medication (liraglutide/Saxenda), a combination of both, or placebo. The greatest weight loss occurred in the first 8 weeks with TDR/VLCD.
The study highlights the importance of combining diet, exercise, and medication to achieve lasting weight loss.
Another recent study has shown that a low-calorie diet before starting weight loss medications like Tirzepatide or Semaglutide can significantly increase effectiveness. The study found that individuals who first followed a low-calorie diet experienced a total weight loss of 35%, compared to 25% in those who only received medication.
"If the result is the same, researchers hope it could help change practices when people begin using weight loss medication."
Read more here about how this combination of a low-calorie diet and weight loss medication can deliver good results: Weight loss medication can become even more effective with "simple interventions," according to new research - TV 2.
